What does ACE do to humans?

Because acepromazine is not used in humans, it is more difficult to predict what symptoms will occur. Based on reports of human ingestions of acepromazine, common symptoms include drowsiness, dizziness, dry mouth, and dystonic reactions (abnormal muscle movements).

How does acepromazine affect humans?

Acepromazine is a phenothiazine derivative that like many veterinary medications is capable of causing significant human toxicity. Toxicity is associated with CNS depression, respiratory depression, and hypotension.

Is acepromazine similar to Xanax?

While Aceorimazine and Xanax medications are rather similar, there are some differences to them that can separate when a vet might prescribe one over the other.

What happens if I take acepromazine?

It is also available as a tablet to be given by mouth. Acepromazine may be taken with food to avoid stomach upset. Common side effects of acepromazine in animals include aggression, biting or chewing, and nervousness. Acepromazine may cause drowsiness.

What is the most common side effect of acepromazine?

The most common and important side effect of acepromazine use is low blood pressure, and in severe cases, it can cause cardiovascular collapse.

How do ACE inhibitors work?

What does acepromazine feel like?

While acepromazine makes patients drowsy, there is some thinking that it heightens the perception of loud noises. Many behaviorists feel that other medications such alprazolam or dexmedetomidine, may be superior in these situations though acepromazine has certainly been the mainstay for pet tranquilization for decades.

What is the controversy with acepromazine?

There is some controversy about the use of this medication in situations that stimulate a panic reaction (thunderstorms, fireworks, etc.) While Acepromazine makes patients drowsy, some veterinary behavioural specialists believe that it heightens the perception of loud noises.

What are the negative side effects of acepromazine?

Does acepromazine calm the mind?

Although acepromazine has several actions that might be useful, it is mostly used as a tranquilizer. Strong anti-nausea properties make this medication an excellent choice for traveling pets who are prone to both excessive restlessness and motion sickness.

How safe is acepromazine?

Acepromazine should be avoided or used with extreme caution in older animals or those with liver disease, heart disease, injury, or debilitation. If it is used in these animals, it should be given in very small doses. In some older animals, a very small dose can have a marked and very prolonged effect.

What is the human equivalent of acepromazine?

It was used in humans during the 1950s as an antipsychotic, but is now almost exclusively used on animals as a sedative and antiemetic. Its closely related analogue, chlorpromazine, is still used as an antipsychotic in humans.

Is acepromazine addictive?

This drug is not addictive. In very few cases, some pets may have an abnormal reaction to Acepromazine and become hyperactive, aggressive or suffer a personality change. This is extremely rare and the effects go away as the drug wears off.

What drug reverses acepromazine?

Clinical significance: Doxapram is effective in reducing the sedative effects of acepromazine over a short period of time.

What class of drug is acepromazine?

Acepromazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. It has a role as a phenothiazine antipsychotic drug.

How long does acepromazine effect last?

Its onset of action is long (15 minutes after intravenous administration, 30 to 45 minutes after intramuscular administration), and it has a long (3 to 6 hours) duration.

Does acepromazine make you sleepy?

Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Is acepromazine a muscle relaxer?

Summary. Acepromazine - "ace" - is a muscle relaxant that is commonly used alone or in combination with other sedatives in horses. Ace can be given IV, IM or orally for mild tranquilization.

Is acepromazine a controlled substance?

Controlled Substances Schedules

In addition, Massachusetts law categorizes as controlled substances those prescription drugs not federally scheduled (such as Xylazine and Acepromazine), and places those drugs into a separate Schedule VI.

Will acepromazine show up on a drug test?

Due to its longer half-life and urinary concentration HEPS, the acepromazine metabolite, is the best candidate for detection of acepromazine usage. Neither HEPS nor the parent acepromazine compound are reliably detected in plasma beyond 24 hours; in most cases urine sampling is preferable.

What are the disadvantages of acepromazine in dogs?

Why not to use acepromazine for dogs?

Common: Acepromazine will cause hypotension, decreased respiratory rate, and bradycardia. Dogs are particularly sensitive to cardiovascular side-effects but cardiovascular collapse also has occurred in cats.

How does acepromazine make dogs feel?

In very few cases, some pets may have an abnormal reaction to Acepromazine and become hyperactive, aggressive or suffer a personality change. This is extremely rare and the effects go away as the drug wears off. Some pets (especially spayed females), may also have mild urinary incontinence while on the drug.

What dogs are sensitive to acepromazine?

Giant Breeds

Some commonly used veterinary drug references suggest that boxers and giant breed dogs may be especially sensitive to the effects of acepromazine. Giant breed dogs often do not require the same mg/kg drug dose as a small breed dog to achieve the same desired effect (i.e. sedation).

Can humans take acepromazine?

Acepromazine is a drug used to sedate animals and is not for human use. Most acepromazine poisonings occur in curious children or when people unintentionally mistake it for their own medication. Common symptoms of acepromazine poisoning include drowsiness and slowed breathing.

What are the negative side effects of acepromazine?