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What happens if MMR is given IM?

All live injected vaccines (MMR, varicella, and yellow fever) are recommended to be given subcutaneously. However, intramuscular administration of any of these vaccines is not likely to decrease immunogenicity, and doses given IM do not need to be repeated.
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Can the MMR vaccine be given IM?

In the U.S., the only measles, mumps, rubella, and varicella vaccines that can be administered IM are M-M-R®II, VARIVAX®, and ProQuad®. Additionally, the MMRV family of vaccines has already been licensed for IM administration in the European Union.
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What happens if varicella vaccine is administered intramuscularly?

Response to vaccines recommended by the subcutaneous route is unlikely to be affected if the vaccines are administered by the intramuscular rather than subcutaneous route. Repeating doses of vaccine administered by the intramuscular route when recommended to be by the subcutaneous route is not necessary (10).
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Is the MMR vaccine subcutaneous or IM?

Each 0.5 mL dose of the M-M-R®II vaccine is administered subcutaneously into the outer part of the upper arm or into the anterolateral area of the thigh. Learn how to reconstitute M-M-R®II in 3 quick steps.
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What happens if an IM injection is given subcutaneously?

In addition, there is a risk that the antigens may be denatured by enzymes if they remain subcutaneously for prolonged period. Subcutaneous injections can lead to localised cellulitis, granuloma formation and abscess.
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MMR Vaccination for Children

How do you treat an IM injection reaction?

How do you treat an injection site reaction?
  1. Warm compress: Warm compresses can be soothing if your muscle is irritated from the injection. ...
  2. Ice packs: Ice packs can help bring down redness, warmth, and swelling. ...
  3. Over-the-counter (OTC) pain relievers: Tylenol or Advil will help with pain bring down swelling and redness.
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What happens if there is blood after an IM injection?

If you see blood in the syringe, you have hit a blood vessel. If you hit a vessel, pull the needle out of the skin. Get rid of the needle and syringe, and prepare a new syringe with medicine. Insert the new needle in a different spot, and check again to see if there is blood.
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Is MMR a live or killed vaccine?

MMR is an attenuated (weakened) live virus vaccine. This means that after injection, the viruses cause a harmless infection in the vaccinated person with very few, if any, symptoms before they are eliminated from the body.
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What needle is used for MMR?

Use a 23–25 gauge needle.
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Is it OK to give varicella IM?

VARIVAX is administered as an approximately 0.5-mL dose by subcutaneous injection into the outer aspect of the upper arm (deltoid region) or the anterolateral thigh. Do not administer this product intravascularly or intramuscularly.
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Why is measles vaccine given subcutaneously?

Subcutaneous: Some vaccines are injected into the layer of fat beneath the skin. This contains fewer blood vessels than muscle, meaning the vaccine is released more slowly, at a constant rate.
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What happens if a vaccine is injected too high in the arm?

Shoulder injury related to vaccine administration (SIRVA) is a rare complication of incorrect vaccine administration, when the vaccine is given too high into the shoulder joint. This can cause shoulder pain and restricted range of movement. Diagnoses include bursitis, tendinitis and rotator cuff tears.
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Where do you inject MMR?

The MMR vaccine is given as 2 doses of a single injection into the muscle of the thigh or upper arm. 2 doses of the vaccine are needed to ensure full protection. Can my child have single measles, mumps or rubella vaccines?
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Is varicella a Subq or IM?

2 doses (0.5 ml each) of varicella vaccine should be given subcutaneously, separated by at least 3 months.
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Which of the following is a contraindication to administration of MMR vaccine?

Contraindications to MMR vaccination do not constitute: Epilepsy with a good response to treatment (at least six months without seizures) A neurological disorder occurred before the start of vaccination.
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How many people have an adverse reaction to the MMR vaccine?

in about 1 in every 24,000 doses of vaccine, a skin rash of small, bruise-like spots develops up to six weeks after vaccination (called idiopathic thrombocytopenic purpura, or ITP). This can also occur after measles or rubella infection, and is more common as a result of the diseases than as a result of the vaccine.
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Is it safe to have 3 doses of MMR?

After reviewing the available evidence on third-dose MMR vaccine,4 ,5 the Advisory Committee on Immunization Practices (ACIP) determined that a third dose of MMR vaccine is safe and effective at preventing mumps during outbreaks.
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What is the death rate of MMR?

Based on historical data, the CDC has estimated that approximately 1 in 4 of cases of measles in the US result in hospitalization, and 1 in 1000 cases results in death.
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Do you pinch the skin for an IM injection?

Insert needle at an 45o angle to the skin. Pinch up on SQ tissue to prevent injecting into muscle. Aspiration before injection is not required.
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Can you hit a nerve with IM injection in deltoid?

Injections that occur below the deltoid muscle can hit the radial nerve and injections that are too far to the side of the deltoid muscle can hit the axillary nerve. If a nerve is hit, the patient will feel an immediate burning pain, which can result in paralysis or neuropathy that does not always resolve.
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What happens if you miss the deltoid muscle?

If the person administering the vaccine misses the deltoid and inserts the needle too high on the shoulder, this can lead to shoulder pain signifying a potentially-serious form of SIRVA.
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How do you know if you did an IM injection wrong?

Call Your Doctor

Medication is injected into the wrong area. Redness, swelling, increasing pain, excessive bleeding, or any discharge from the injection site. Rash or hives develop.
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Can an IM injection hit a vein?

Measure this site carefully, because an injection given in the wrong place could hit a nerve or blood vessel. Uncover one buttock.
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Why is my IM injection bleeding so much?

If there is blood, it means the needle is in a blood vessel and not a muscle. Withdraw and start over with a new needle, syringe, and injection site. If there is no blood, the needle is in the correct position.
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